PharmaCytics B.V.

PharmaCytics B.V. is located in Nijmegen, Netherlands on Transistorweg 5. PharmaCytics B.V. is rated 3 out of 5 in the category pharmaceutical company in Netherlands. PharmaCytics offers a drug delivery solution, based on an advanced prodrug approach. The technology exploits intestinal transporter proteins as carriers for drug conjugates in which a transporter substrate is linked to a drug moiety. The drug conjugates are recognized and transported by specific nutrient transporter proteins that are abundantly present in the gut membrane. The transporter substrate is designed such that it can be cleaved off by metabolic enzymes, naturally present in the intestinal wall, the liver or the blood, releasing the active drug. Our technology deals with multiple issues associated with drug absorption at the same time, as opposed to many currently existing techniques that often focus on solubility only. The application of our technology is not limited to a specific indication; it can be applied broadly and mainly depends on the chemical structure of the compound. Within PharmaCytics there is ample experience in this specific area. The technology can be applied in all stages of the Drug Development life cycle: • For marketed products it potentially extents or renews the patent position and/or it can be used to reposition the drug • The latter also emphasizes the importance of this technology for the generic market • Revival of New Chemical Entities (NCE) that were put on hold • In the development phase it can be used to improve the formulation PharmaCytics believes that this potentially means that current revenues can be protected or even expanded and in case of NCE’s future revenues could be generated sooner. The company: PharmaCytics has a dedicated and very experienced team of medicinal chemists. We are located at one of the most important life sciences clusters in the Netherlands, the Novio Tech Campus in Nijmegen, where we have fully equipped chemistry labs. Next step: PharmaCytics is happy to discuss possibilities to use our expertise for your marketed, research or development products to improve on a bioavailability issue.